2006-07-25

51 Cr‐EDTA clearance was measured with the standard bolus injection technique and glomerular filtration rate (GFR) was calculated by the single‐sample method described by Jacobsson. Mannitol, 0·25 g kg −1 body weight (150 mg ml −1 ), was infused for 4–14 min and blood samples taken at 1‐, 2‐, 3‐ and 4‐h ( n = 24) or 2‐, 3‐, 3·5‐ and 4‐h after infusion ( n = 17).

The calculation of 51 Cr‐EDTA clearance by method II (Cl II) was based on a close relation between 51 Cr‐EDTA clearance and the reciprocal apparent volume of distribution normalized with respect to body surface area. It was demonstrated that the two methods were closely related. that the 51Cr-EDTA clearance corresponds very closely with the inulin clearance when estimated by the standard infusion technique, quoting r values of 0.995 and 0.992, respectively. The renal handling of 51Cr-EDTA and inulin would therefore appear to be identical.

51cr edta clearance method

Furthermore, this method is technologically cumbersome,requiring accuratelytimedurine collections, preferably over 24 hours. Measurements of serum creatinine and /32 microglobulin arebothclosely relatedto5tCr- 2020-03-01 · Renographic Gates’ method and serum creatinine equations are used for GFR measurement. • In comparative studies patients with diabetes are under-represented or missing. • A close agreement is shown between 51 Cr-EDTA and 99m Tc-DTPA plasma clearance. • 99m Tc-DTPA plasma clearance can replace 51 Cr-EDTA in patients with type 2 diabetes.

Plasma clearance rate of 51Cr-EDTA provides a precise and convenient technique for measurement of glomerular filtration rate in diabetic humans J Am Soc Nephrol . 1996 Jan;7(1):118-27.

c:a 800 S-cystatin C-analyser och 720 iohexol-clearance. Njurfunktionens A more accurate method to estimate glomerular (compensated method) bestämt avdraget. Övriga svenska något bättre med 51Cr-EDTA-clearance än vad den ursprungliga formeln ger.

Plasma clearance of 51 Cr‐EDTA (51 Cr‐EDTA‐Cl) was described in 1967 by Garnett et al. as an alternative method to measure GFR and has been used in clinical nephrology since then. In spite of its use for almost four decades, studies comparing In‐Cl and 51 Cr‐EDTA‐Cl have either not included renal transplant recipients [ 12 - 22 ] in their population study or included only a few [ 23 ].

Multiple sample methodThe plasma clearance of 51 Cr-EDTA for the entire group of cats ranged between 0.4 and 8.7 ml/min/kg when normalised for body weight (mean AE SD, 3.7 AE 2.5 ml/min/kg).The mean AE SD for the normal cats yielded to 2.4 AE 1.3 ml/min/kg. The mean clearance value for the hyperthyroid cats AE SD was 4.3 AE 1.9 ml/min/kg. Patients with advanced epithelial ovarian cancer were treated with first-line carboplatin (AUC = 7, using the 51Cr EDTA [edetic acid] clearance method) and escalating doses of paclitaxel. Thrombocytopenia was mild and was significantly less when the paclitaxel dose was 175 mg/m2 versus 150 mg/m2. AIM: The aim of this study was to evaluate the efficacy of 51Cr-EDTA clearance to tailor the carboplatin dose in two different therapeutic regimens of advanced epithelial ovarian cancer. MATERIALS AND METHODS: 14 patients entered the study, eight treated by carboplatin (C) alone and six by C and paclitaxel (P).

The mean clearance value for the hyperthyroid cats AE SD was 4.3 AE 1.9 ml/min/kg.
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database of 51Cr-ethylenediaminetetraacetic acid (51Cr-EDTA) renal clearance determinations using the two blood sample method, 598 patients, aged 1 week to 90 years, were selected. The results of the 51Cr-EDTA slope intercept clearance of the two blood sample method were used as reference.

Renal clearance of DTPA, renal clearance of iohexol, and plasma clearance of inulin had sufficient accuracy (limited evidence). y = 1.28~ - 2.49) who found a very close relationship between inulin clearance and 51Cr-EDTA clearance (r = 0.992, y = 1.02~ - 0.95).
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Cystatin C. Endogen A more accurate method to es- timate glomerular filtration Assessing glomerular filtration rate (GFR) in critically ill patients with acute kidney injury (AKI) - true GFR versus urinary creatinine clearance Beräkning av GFR genom plasmaclearance av 51Cr-EDTA och johexol är enklare än bestämning av renal clearance med inulin.